He studied at the School of Fine Arts from 1942 to 1946 under Kostas Dimitriadis and Michalis Tombros. From 1960 to 1962, with a scholarship from the University of Athens, he also studied at the School of Fine Arts in Paris under Henri-Georges Adam.

He presented his work in solo exhibitions in Greece and participated in group events in Greece and abroad. He also took part in the Sao Paulo Biennale in 1969.

The majority of Antonis Karachalios’ work has a realistic starting point, although, mainly in free compositions, it becomes more abstract. In most of his works he is focused on the human figure, on a more limited scale, however, he also dealt with zooplastics, creating full-length or fragmentary forms of animals, which are attributed to characteristic poses.

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