He studied sculpture (1956-1962) with Yannis Pappas at the Athens School of Fine Arts. In 1964-1974, he worked at Nikos Kerlis’s foundry and later at the archaeological museums in Delphi and Olympia.

His work has been shown in solo and group exhibitions, including Greek national exhibitions, the Paris Biennale Internationale des Jeunes Artistes (1967), the Sao Paulo Biennale (1971) and the Budapest Biennale (1971).

Inspired by the human figure and human condition, and using plaster, wax, clay and bronze, Spyros Katapodis blended figurative and abstract approaches as well as cubist and constructivist elements, producing emotionally charged compositions with surrealistic and expressionistic overtones.