She studied sculpture at the Athens School of Fine Arts (1966-1972) with Thanassis Apartis, Yannis Pappas and Dimitris Kalamaras as well as theatre set design with Vassilis Vassiliadis. During 1975-1978, she went for further studies at the Ecole des Beaux Arts in Paris, attending sculpture courses with Cesar and costume design courses with Marcel Gili.

She has presented drawings for her works in solo exhibitions and has participated at the Salon du mai in Paris, the Alexandria Biennale (1980) and Panhellenic exhibitions.

Inspired by Greek nature, the architecture of the Aegean and Archaic sculpture, Aspassia Papadoperaki’s works are distinguished for the architectural quality of their forms, their measure, proportions and symmetry – a concept she has explored in depth.